Christiaan Huygens wrote to Henry Oldenburg doubting Leeuwenhoek's observations of globules

January 20, 1675

Christiaan Huygens wrote in French to Oldenburg from Paris (trans. from Oldenburg's Correspondence, v. XI, p. 163); also in Huygens's Oeuvres Complètes, v. 7, p. 400. The manuscript is to be found in London, Royal Society, Early Letters, H1.81. It was read to the Royal Society at the meeting of 28 January 1675; Birch's History, vol. 3, p. 179.

A letter of Mons. Huygens to Mr. OLDENBURG, dated at Paris, 30th January, 1675, was read, giving notice of a invention of watches by himself, the secret of which he conceals in an anagram.

Huygens wrote:

I should also very much like to know how much faith there is among you in the observations of our Mr. Leeuwenhoek, who turns everything into little globules. As for me, after having tried in vain to see certain things which he sees, I very much doubt whether these are deceptions of his vision. And even more so when he claims to discover the particles of which water, wine, and other liquids are composed, with which, he told my father, he was occupied.